[18F]tetrafluoroborate as a PET tracer for the sodium/iodide symporter: the importance of specific activity
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چکیده
منابع مشابه
[18F]tetrafluoroborate as a PET tracer for the sodium/iodide symporter: the importance of specific activity
BACKGROUND [(18)F]BF4 (-), the first (18)F-labelled PET imaging agent for the sodium/iodide symporter (NIS), was produced by isotopic exchange yielding a product with limited specific activity (SA, ca. 1 GBq/μmol) posing a risk of sub-optimal target-to-background ratios (TBR) in PET images due to saturation of NIS in vivo. We sought to quantify this risk and to develop a method of production of...
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ژورنال
عنوان ژورنال: EJNMMI Research
سال: 2016
ISSN: 2191-219X
DOI: 10.1186/s13550-016-0188-5